Immediate type hypersensitivity and late phase reaction occurred consecutively in a patient receiving ethambutol and levofloxacin

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منابع مشابه

Immediate type hypersensitivity and late phase reaction occurred consecutively in a patient receiving ethambutol and levofloxacin

Background We experienced a rare case of immediate type hypersensitivity and late phase reaction to anti-tubercular therapy consisting of ethambutol and levofloxacin, which occurred in close succession, giving the appearance of a single, continuous reaction to one drug. Case presentation The patient was a man in his 70's who began therapy consisting of isoniazide, rifampicin, and ethambutol f...

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Delayed-type hypersensitivity reaction to ethambutol and isoniazid.

A 24-year-old woman had recently started antitubercular therapy with isoniazid, ethambutol and rifampicin. This therapy was discontinued 2 weeks later due to an itchy, desquamative, erythematous, papular rash, with painful crusts and excoriations, spreading from the face and hands to the rest of the body. 5 days after withdrawal of all drugs, widespread desquamation and exfoliation with predile...

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Hypersensitivity Reaction and Tolerance Induction to Ethambutol

Tuberculosis remains the leading cause of death worldwide from any infectious agent and the alarming increase in the annual incidence of new cases has been described as a global emergency. Mycobacterium infection requires simultaneous administration of multiple drugs. Although the majority of treatment courses progress with minor side effects, adverse reactions to antituberculosis drugs occur i...

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A novel murine model of late-phase reaction of immediate hypersensitivity

We describe here a novel experimental model of late-phase reaction of immediate hypersensitivity developed in mice. It consists of introducing small fragments of heat-coagulated hen egg white into the subcutaneous tissue of mice. After 14 days, animals challenged with purified ovalbumin into the footpad presented an immediate swelling of the paw peaking at 30 min, followed by two peaks of swell...

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Cross sensitivity between ciprofloxacin and levofloxacin for an immediate hypersensitivity reaction

Seven years old male child (24 kg weight) diagnosed as a case of sub acute appendicitis treated with ciprofloxacin, immediately developed multiple erythmatous papules. Reaction subsided after withholding ciprofloxacin and treatment with dexamethasone and chlorpheneramine maleate. It was developed again when treated with levofloxacin and subsided after withdrawal. IgE binding at 7(th) position o...

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ژورنال

عنوان ژورنال: Allergy, Asthma & Clinical Immunology

سال: 2018

ISSN: 1710-1492

DOI: 10.1186/s13223-018-0237-x